A platform for liposomal drug delivery

Abstract

Liposome has been used as a carrier to transport a wide variety of compounds in its aqueous compartment. The clinical
potential of liposomes as a vehicle for replacement therapy in genetic deficiencies of lysosomal enzymes was first
established in 1970. Liposomes are surfactants, sphingolipids, glycolipids, long chain fatty acids and even membrane
proteins and drug molecules or it is also called vesicular system. These are different in size, composition and charge. These
are a drug carrier variety of molecules such as proteins, nucleotides and even plasmids. Some drugs are also formulated as
liposomes to improve their therapeutic index, stability and compatability. The vesicular drug delivery systems such as
liposomes, niosomes, transfersomes, and pharmacosomes were developed. In this paper main focus on liposomal
classification, various method of preparation, evaluation parameter , merits, recent status and scope.