FABRICATION AND CHARACTERIZATION OF GRAPHENE OXIDE NANOPARTICLES AS PLATFORM FOR DRUG DELIVERY

Abstract

Graphene oxide [GO] nanoparticles have rapidly grown a new type of nanomaterial for drug delivery. A novel approach to
fabricate graphene oxide nanoparticles has been reported. The graphene oxide synthesized by oxidation of graphite in
H2SO4: H3PO4 [9:1] with continuous stirring for 12hr. Graphene oxide contribute as biomaterial for biomedical application
due to its structural features as two dimensional, planar structures with high surface area, good biocompatibility and it also
acts as filler. The synthesized GO characterized by using SEM, DSC, FT-IR, Malvern Zetasizer, and UV-spectroscopy. Due
to its multifunctional properties GO acts as nanocarrier and most preferably used as novel nanomaterial for anticancer
therapy with high drug loading capacity and for the design of advanced drug delivery system and delivery of a broad range
of therapeutics.