AN INCISIVE REVIEW ON MICROSPHERES AS DRUG DELIVERY SYSTEM

Authors

  • Navdeep Bharti Department of Pharmaceutics, CT institute of Pharmaceutical Sciences, Shahpur, Jalandhar.
  • Gagandeep Singh Dhatt Department of Pharmaceutics, CT institute of Pharmaceutical Sciences, Shahpur, Jalandhar.
  • Surya Prakash Gautam Department of Pharmaceutics, CT institute of Pharmaceutical Sciences, Shahpur, Jalandhar.
  • Narinder Singh Department of Pharmaceutics, CT institute of Pharmaceutical Sciences, Shahpur, Jalandhar.

Keywords:

Microspheres, Polymer, Specificity, Technique and Controlled release

Abstract

The objective of any medication conveyance framework is to give a helpful measure of medication to the best possible site in the body and after that keep up the coveted medication focus. An all-around composed controlled medication conveyance framework can defeat some of issues of routine treatment and improve restorative viability of the given medication. There are different methodologies in conveying helpful substance to the objective site in maintained and controlled discharge. One such approach is utilizing microspheres as transporters for drug. Microspheres got much consideration for delayed discharge, as well as for focusing of anticancer medications. In future by consolidating different systems, microspheres will locate the focal spot in novel medication conveyance, especially in unhealthy cell sorting, diagnostics, quality and hereditary materials, safe, focused on and viable in vivo conveyance and supplements as small forms of infected organ and tissues in the body.

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References

Singh P, Prakash D, Ramesh B, Singh N, Tamizh mani T. Biodegradable Polymeric Microspheres as Drug Carriers; A Review.Ind J of Novel Drug delivery.2011;3(2):70-82.

Ghulam M, Mahmood A, Naveed A, Fatima RA. Comparative study of various microencapsulation techniques and effect of polymer viscosity on microcapsule characteristics, Pak.J.Sci.2009:291-300.

Li SP, Kowalski CR, Feld KM, Grim WM. Recent Advances in Microencapsulation Technology and Equipment. Drug Dev Ind.Pharm. 1988;14: 353-376

DandagiPM, MastiholimathVS,Patil MB, Gupta MK. Biodegradable micro particulate system of captopril. IntJ of Pharmaceutics. 2006; 307:83-88.

Kunchu K, Veera R .Albumin Microspheres: A Unique system as drug delivery carriers for non-steroidal anti-inflammatory drugs. 2010;5(2):12.

Najmuddin M., Ahmed A., Shelar S, Patel V, Khan T. Floating Microspheres Of Ketoprofen: Formulation and Evaluation.Int J of Pharmacy and Pharmaceutical sciences. 2010; 2(2):83-87.

Dandagi PM, Mastiholimath VS, Patil MB, Gupta MK. Biodegradable micro particulate system of captopril. IntJ Pharma.2006; 307:83-88.

Ranama Z, Nath LK, Anwarul H, Tarasankar M, Prasant KC, Bhupendra S. Formulation and in vitro evaluation of natural polymers based microsphere for colonic drug delivery. International J Pharma and Pharma Sci.2010; 2(1):211-219.

Jain NK.Controlled and Novel drug delivery, 04 Edition, CBS Publishers New Delhi, India; 21,236-237.

Imran A, Kayyum T, Sadhana S, Thube M, Ankit S. Review on Microspheres. International J Pharma Res Allied Sci.2012; 1(1):24-33.

Saravana KK, Jaya Chandra RP, Chandra Sekhar KB. A Review on Microsphere for Novel drug delivery System. J Pharm Res.2012; 5(1):420-424.

Sipai AB, Vandanayadav M, Mamatha Y, Prasanth VV.Mucoadhesive Microsphere An overview. American J Pharm Res.2012; 2(1):237-258.

Shiv SH, Jian A, Ritesh P, Kaushal A.Formulation and evaluation of mucoadhesive microsphere of ciprofloxacin. J Adv Pharma Edu and res.2011.1 (4):214-224.

Dutta P, Struti J, Niranajanpatra CH, Bhaojirao ME.Floating Microsphere: Recent Trends in the Development of Gastro retentive Floating Drug Delivery System. Int J of Pharma Sci & nanotech.2011; 4(1):1293-1306.

Alexander K, Andrianov, Lendon GP. Polymeric carriers for oral uptake of micro particulates. Adv Drug Delivery Rev.1998; 34:155-170.

Patel NR, Patel DA, Bharadia PD, Pandya V.Microsphere as a novel drug delivering. J of Pharm & Life Sci.2011; 2(8):992-997.

Sunitha S, Amareshwar P, Santosh KM, Chakravarti P.Preparation and Evaluation of Tramadol Hydro-chloride microspheres by phase separation coacervation technique using various solvents and non-solvents. J of Global Pharm Tech.2011; 3(4):33-41.

Mahajan H, Gattani S, Surana S. Spray Dried Mucoadhesive Microspheres of Ondansetron for Nasal Administration. Int J of Pharma Sci and Nanotech.2008; 1(3):267-273.

Mathew ST, Devi GS, Prasanth VV, Vinod B.NSAIDs as microspheres. The Internet J of Pharma.2008; 6(1):67 – 73.

Lakshmana PS, Shirwaikar A, Kumar A.Formulation and evaluation of sustained release microspheres of rosin containing aceclofenac.Ars Pharm.2009; 50(2):51-62.

Das MK, Rao KR.Evaluation of Zidovudine encapsulated ethyl cellulose microspheres prepared by Water -Oil-Water double emulsion solvent diffusion technique. Acta Poloniae Pharmaceutica & Drug Res.2006; 63(2):141-148.

Vikrant KN, Gudsoorkar VR, Hiremath SN, Dolas RT, Kashid VA. Microspheres novel drug delivery system: An overview.IJPCS.2012; 1(1):113-127.

Lopez CR, Portero A, Vila-Jato JC, Alonso MJ. Design and Evaluation of mucoadhesive bilayered devices for buccal drug delivery.J.control.Rel. 1998;55: 143- 52.

Alagusundaram M, Chetty MSC, Umashankari K, Badarinath AV, Lavanya C, Ramkanth S. Microspheres as a Novel Drug Delivery System- A Review. Int. J. of Chem. Tech Res.2009;1: 526-34.

Rathone MJ. Human buccal absorption. A method for Estimating the transfer kinetics of drugs across the human buccal membrane. Int. J. pharm. 1991;69: 103

Mathew ST, Devi GS, Prasanth VV, Vinod B. Suitability of factorial design indetermining the processing factors affecting entrapment efficiency of albumin microspheres.J Pharma Res.2010;3(5):1172-1177.

Published

2016-11-05
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Navdeep Bharti, Gagandeep Singh Dhatt, Surya Prakash Gautam, and Narinder Singh. “AN INCISIVE REVIEW ON MICROSPHERES AS DRUG DELIVERY SYSTEM”. International Journal of Pharmaceutics and Drug Analysis, vol. 4, no. 11, Nov. 2016, pp. 486-93, https://www.ijpda.org/index.php/journal/article/view/257.

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