Determination of Secondary Metabolites and Antioxidant Activity of Murraya koenigii
Keywords:
Murraya koenigii, Phytochemicals, free radical, scavenging activityAbstract
This study is to quantify the secondary metabolites and the antioxidant potential of ethanolic extract of Murraya koenigii. The ethanolic leaves extract of Murraya koenigii was analysed by HPLC and GC to determine various Phytochemicals. The free radicals scavenging activity of extract was determined by using DPPH, NO and Super oxide radicals generated in vitro. The ethanolic leaves extract of M. koenigii was found to contain alkaloids (7.20mg/g), tannins (2.02mg/g), phenols (5.36mg/g) and flavonoids (3.42mg/g). The major flavonoids detected were quercetin and rutin. The ethanolic extract of M. koenigii was found to possess significant free radical scavenging activity against DPPH, NO and SOD anions. The medicinal property of Murraya koenigii may be attributed to the presence of flavonoids and phenolic compounds with rich antioxidant potential. The therapeutic effect of this plant may be accounted for its counteracting action on free radicals in vivo.
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