Bilateral lower limb cellulitis accompanied by acute flare psoriasis:a case report

Authors

  • Shashidharan Menon School of Pharmacy, KPJ Healthcare University, Lot PT 17010, Persiaran Seriemas Utama, Kota Seriemas, 71800 Nilai, Negeri Sembilan, Malaysia.
  • Jaasminerjit Kaur School of Pharmacy, KPJ Healthcare University, Lot PT 17010, Persiaran Seriemas Utama, Kota Seriemas, 71800 Nilai, Negeri Sembilan, Malaysia.
  • Krupavaram.B School of Pharmacy, KPJ Healthcare University, Lot PT 17010, Persiaran Seriemas Utama, Kota Seriemas, 71800 Nilai, Negeri Sembilan, Malaysia.
  • Mathangopal Rawee School of Pharmacy, KPJ Healthcare University, Lot PT 17010, Persiaran Seriemas Utama, Kota Seriemas, 71800 Nilai, Negeri Sembilan, Malaysia.

DOI:

https://doi.org/10.47957/ijpda.v13i1.624

Keywords:

Cellulitis, Psoriasis flare, Methotrexate, Lower limb swelling, Fever

Abstract

Mr. K, an 82-year-old Chinese man, was admitted due to worsening bilateral lower limb swelling over the past week and an exacerbation of psoriatic lesions over the past three weeks. After noticing swelling on May 15, he visited a clinic for his Methotrexate regimen for psoriasis. On May 16, he sought help at the Emergency Department at HUKM but was discharged without medication. His condition worsened, and on May 18, he became febrile and returned to the HUKM Emergency Department. Upon examination he was diagnosed with bilateral lower limb cellulitis with acute flare psoriasis as the primary diagnosis.

Downloads

Download data is not yet available.

References

Anne R Mason et al. (2013, March 28). Topical treatments for chronic plaque psoriasis. Retrieved from https://pubmed.ncbi.nlm.nih.gov/23543539

April W. Armstrong, Charlotte Read. (2020, May 19). Sci-hub | Pathophysiology, clinical presentation, and treatment of psoriasis. JAMA, 323(19), 1945 | 10.1001/jama.2020.4006. Retrieved from https://sci-hub.se/10.1001/jama.2020.4006

Babita Gupta, Neha Garg and Rashmi Ramachandran. (2017, January). Vasopressors: Do they have any role in hemorrhagic shock? Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles PMC5374828/

Bennie Ray Upchurch. (2021, October 17). Upper gastrointestinal bleeding (UGIB) treatment & management: Approach considerations, proton-pump inhibitors, therapeutic endoscopy. Retrieved from https://emedicine.medscape.com/article/18 7857-treatment?form=fpf

Br J Gen Pract. (2018, December). Management of cellulitis: Current practice and research questions. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles /PMC6255235/

Brandon D. Brown, Kristen L. Hood Watson. (2023, August 7). Cellulitis - StatPearls - NCBI bookshelf. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK 549770/

Bruner, C., Feldman, S., Ventrapragada, M., & Fleischer, A. (2003). A systematic review of adverse effects associated with topical treatments for psoriasis - Database of abstracts of reviews of effects (DARE): Quality-assessed reviews - NCBI bookshelf. Retrieved from

https://www.ncbi.nlm.nih.gov/books/NBK 70134/

Dennis L. Stevens et al. (2014, April 21). Sci- hub | Executive summary: Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America. Clinical infectious diseases, 59(2), 147–159 | 10.1093/CID/ciu444. Retrieved from https://sci-hub.se/10.1093/cid/ciu444

Jarett C Worden, Kirollos S Hanna. (2017, February 2). Optimizing proton pump inhibitor therapy for treatment of nonvariceal upper gastrointestinal

bleeding. Retrieved from https://read.qxmd.com/read/28122752/opti mizing-proton-pump-inhibitor-therapy- for-treatment-of-nonvariceal-upper- gastrointestinal-bleeding?redirected=slug

L. Stein Gold, C. Paul, R. Romiti. (2020, October 27). Efficacy and safety of fixed- dose combination calcipotriol/betamethasone dipropionate foam for the treatment of psoriasis | 10.1111/jdv.17028_Scihub. Retrieved from https://www.bothonce.com/10.1111/jdv.170 28

Mahboob Rahman et al. (2012, October 1). Acute kidney injury: A guide to diagnosis and management. Retrieved from https://www.aafp.org/pubs/afp/issues/2012

/1001/p631.html

Malaysia National Antimicrobial Guideline. (2019). Retrieved from https://pharmacy.moh.gov.my/sites/defaul t/files/document-upload/nag-2019-latest-9- dis-2020_0.pdf

Patrick Yachimski et al. (10, May). Proton pump inhibitors for prophylaxis of nosocomial upper gastrointestinal bleeding: The impact of standardized guidelines on prescribing practice. Retrieved from

https://www.ncbi.nlm.nih.gov/pmc/articles

/PMC3758922/

Pragya A. Nair; Talel Badri. (2023, April 3). Psoriasis - StatPearls - NCBI bookshelf. Retrieved from

https://www.ncbi.nlm.nih.gov/books/NBK 448194/

Sandra Nelson. (2023, December 15). UpToDate: Treatment of Acute cellulitis and erysipelas in adults. Retrieved from https://www.uptodate.com/contents/acute- cellulitis-and-erysipelas-in-adults- treatment

Tadhg Sullivan. (2018, April). Diagnosis and management of cellulitis. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles /PMC6303460/

Evaluation of ethanolic root extract of Allium cepa. l for analgesic and anti-inflammatory activities in animal models.2020 DOI https://doi.org/10.37022/WJCMPR.20 2 0.02017

Babu, A. K., Kumar, M. P., Krupavaram, B., Mandadi, S. R., Lakshmi, Manikandhan, R., Haque, M. A., & Sultana, R. (2022). Diabetic foot ulcer, antimicrobial remedies and emerging strategies for the treatment: An overview. International Journal of Health Sciences, 6(S3), 2835–2850. https://doi.org/10.53730/ijhs.v6nS3.6199

Published

2025-03-31
Statistics
80 Views | 40 Downloads
Citatons

How to Cite

Shashidharan, M., K. Jaasminerjit, K. B, and M. Rawee. “Bilateral Lower Limb Cellulitis Accompanied by Acute Flare psoriasis:A Case Report”. International Journal of Pharmaceutics and Drug Analysis, vol. 13, no. 1, Mar. 2025, pp. 42-47, doi:10.47957/ijpda.v13i1.624.

Issue

Section

Case Reports
Share |