A review on ethosomes promising as novel drug delivery systems

Muskan Muskan; Rajesh Kumar; Pal Singh Ajeet; Pal Singh Amar

doi:10.47957/ijpda.v13i3.649

Authors

Muskan Department of Pharmaceutics, St. Soldier Institute of Pharmacy, Lidhran Campus, Behind NIT (R.E.C.), Jalandhar –Amritsar by pass, NH-1, Jalandhar -144011, Punjab, India
Rajesh Kumar Department of Pharmaceutics, St. Soldier Institute of Pharmacy, Lidhran Campus, Behind NIT (R.E.C.), Jalandhar –Amritsar by pass, NH-1, Jalandhar -144011, Punjab, India
Ajeet Pal Singh Department of Pharmacology, St. Soldier Institute of Pharmacy, Lidhran Campus, Behind NIT (R.E.C.), Jalandhar –Amritsar by pass, NH-1, Jalandhar -144011, Punjab, India.
Amar Pal Singh Department of Pharmacology, St. Soldier Institute of Pharmacy, Lidhran Campus, Behind NIT (R.E.C.), Jalandhar –Amritsar by pass, NH-1, Jalandhar -144011, Punjab, India.

DOI:

https://doi.org/10.47957/ijpda.v13i3.649

Keywords:

Ethosomes, vesicular carriers, skin permeation, transdermal drug delivery, topical application, phospholipids, ethanol, drug delivery systems, stability, characterization

Abstract

Ethosomes are new lipid-based vesicular carriers that improve medication penetration across the stratum corneum due to their high ethanol concentration. Because of this special characteristic, ethosomes may efficiently transport hydrophilic and lipophilic medications via topical or transdermal routes deep into the skin or even into the systemic circulation. Improved skin penetration, adaptability in drug loading, and biocompatibility are only a few benefits of ethersomes. Vesicle stability issues, such phospholipid oxidation and vesicle fusion during storage, are still problematic, nevertheless. To describe ethosomal formulations and guarantee their quality, effectiveness, and safety as drug delivery vehicles, a range of assessment techniques are used.

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A review on ethosomes promising as novel drug delivery systems

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